Enzyme Commission Number
EC 2.1.1.296
Product Overview
High-quality enzyme products.
Well-established quality management system.
Reaction
S-adenosyl-L-methionine + a 5′-(N7-methyl 5′-triphosphoguanosine)-(2′-O-methyl-purine-ribonucleotide)-(ribonucleotide)-[mRNA] = S-adenosyl-L-homocysteine + a 5′-(N7-methyl 5′-triphosphoguanosine)-(2′-O-methyl-purine-ribonucleotide)-(2′-O-methyl-ribonucleotide)-[mRNA]
Systematic Name
S-adenosyl-L-methionine:5′-(N7-methyl 5′-triphosphoguanosine)-(2′-O-methyl-purine-ribonucleotide)-ribonucleotide-[mRNA] 2′-O-methyltransferase
Function
The enzyme, found in higher eukaryotes including insects and vertebrates, and their viruses, methylates the ribose of the ribonucleotide at the second transcribed position of mRNAs and snRNAs. This methylation event is known as cap2. The human enzyme can also methylate mRNA molecules where the upstream purine ribonucleotide is not methylated (see EC 2.1.1.57, methyltransferase cap1), but with lower efficiency.
Other name
MTR2; cap2-MTase; mRNA (nucleoside-2′-O)-methyltransferase (ambiguous)
Production Methods
Fermentation
Package
on customer request
Applications
Research Use
Storage
Should be stored in a dry and cool place, avoiding high temperature.
Appearance / Form
powder or liquid
Odor
Normal microbial fermentation odour.
WARNINGS
Keep sealed after use every time to avoid microbial infections and inactivation of enzymes until its finish.
Description
Microbial enzymes have been used in a large number of fields, such as chemical, agricultural and biopharmaceutical industries. Our enzyme production services are based on bacteria, fungi, and yeast, from strain selection, optimization, and process development to scale-up production.
