Yeast Fermentation

Creative Biogene provide high-quality yeast fermentation services at different scales, especially for industrial and cGMP fermentation. Our products and integrated solutions maximize yields and cell performance in biotechnological production systems for the world's leading pharmaceutical and biotechnology companies.

Yeast fermentation has a wide range of industrial applications. Yeast expression systems allow efficient production of secreted and intracellular targets. In addition, yeast provides the advantage of post-translational modifications, which may be beneficial for some recombinant proteins. Various host cells and vectors are available for yeast expression. We also have some robust secretion signal sequences to ensure the highest secretion of proteins. In addition, we leverage a wealth of technical and manufacturing expertise in cell culture media supplements. Our application labs develop optimized formulations to enhance the performance of a variety of yeast cell lines.

Alcoholic Fermentations

Alcoholic fermentation is a complex biochemical process during which yeasts convert sugars to ethanol, carbon dioxide, and other metabolic byproducts that contribute to the chemical composition and sensorial properties of the fermented foodstuffs. Yeast plays a vital role in the production of all alcoholic beverages and the selection of suitable yeast strains is essential not only to maximize alcohol yield, but also to maintain beverage sensory quality.

Biofuels and Other Chemicals Production

The fermentation processes of substrates such as xylose are also of high interest on an industrial level. They allow the environmental cost of efficient production of biofuels and other advanced chemicals to be reduced. Some interesting approaches have been made to reprogram yeast for use in these bioprocesses. Biofuel production by recombinant Saccharomyces cerevisiae strains with essential genes and metabolic networks for xylose metabolism has been developed.

Service Options for Fermentation Projects

Our experts have utilized microbial systems to express a wide variety of proteins.

Product Types

Other Options for Fermented End-products

Yeast Strain Options

Fermentation Plants

2-5 L fermenters, incubation chambers, master cell bank, etc. Cutting edge technology focused on versatility for all types of development projects (up to 2,000 L fermenter). Different fermentation chamber capacities.
Auxiliary tanks and continuous sterilizers.
Distillation columns.

Choose Your Configuration

Creative Biogene offers a diverse array of configurations in solid, liquid, and powder formats to deliver on your off-the-shelf and contract fermentation needs.

Packaging sizes range from small and ready-to-use to bulk super sacks.
Powders are also available in water-soluble packets for fast, hassle-free dosing.
Liquids are available in quarts to tanker loads and every packaging size in between.
We offer non-formulated liquids for custom formulations and fully formulated liquids and concentrates for further formulation or dilution.
Dissolution rates depend on the solid's chemistry, size, aspect ratio, and the temperature and flow of the placement environment.
We provide diverse extruded solid shapes in sizes suited to institutional as well as municipal and industrial applications.

Creative Biogene has an unparalleled track record in working with many different types of products and providing highly complex fermentation services. We have extensive experience with processes developed internally, as well as those transferred into our facilities for scale up. Our licensed facilities are prepared to meet preclinical to marketed production needs.

If you are interested in our services, please contact us for more details.


  1. Maicas S. The Role of Yeasts in Fermentation Processes. Microorganisms. 2020 Jul 28;8(8):1142.
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