EggNOG (Evolutionary Genealogy of Genes: Non-supervised Orthologous Groups) database collects 5,090 organisms (477 eukaryotes, 4,445 representative bacteria and 168 archaea) and 2,502 viruses COG (Clusters of Orthologous Groups of proteins). Each COG is assumed to be from an ancestor, and each protein has an integrated and summarized functional annotation. EggNOG can provide COG at different classification levels, divide these species into 379 taxonomic levels, and the number of each category is represented by the NCBI classification number. EggNOG classified homologous genes for the COG of each species, and carries out multiple sequence alignment, phylogenetic tree construction, HMM file construction and functional annotation for each homologous gene category.
The EggNOG database is an extension of NCBI's COG database, and EggNOG collects more comprehensive species and a larger amount of protein sequence data. The cluster analysis of homologous genes and the description and function classification of each homologous gene class are also carried out.
Fig.1 Functional analyses on OGs of the gut microbiota. Summary of unigenes matched to each EggNOG functional categories present in the gut metagenome datasets. (Wang T, et al. 2020)
Our services in EggNOG analysis include,
In general, our turnaround time is 2-4 weeks depending on the size of your project.
Creative Biogene is a forward-looking research institution in the field of EggNOG analysis. Our advanced analysis platforms are established to provide you with results of good reproducibility. EggNOG database categorizes more comprehensive species and a larger number of protein sequences, enabling the analysis results more accurate. We will uphold the belief of pursuing high quality and the spirit of professionalism and dedication to provide you with our optimal service.
If you are interested in our services, please contact us for more details.