consultation 

GO Analysis

The GO (Gene Ontology) database was established by the Gene Ontology Association in 1988. The database classifies and aggregates all the research results related to genes in the world. GO standardizes the biological terms of genes and gene products in different databases, and uniformly defines and describes the functions of genes and proteins. GO has developed a standard language (ontologies) with a tertiary structure in order to make the functional description of gene products in various databases consistent, which can classify and annotate genes and gene products in the following three aspects,

  • BP (Biological Process) - Orderly combination of molecular functions to achieve broader biological functions.
  • MF (Molecular Function) - Function of individual gene products.
  • CC (Cellular Component) - Structure and location of subcellular, as well as macromolecular complex.

Below these three major branches, there are many small levels. The larger the level number is, the more detailed the function description will be. The top three branches are regarded as level1, and the subsequent levels are level2, level3 and level4. The GO annotation provides an overview of the functional classification of all gene products of a species. At present, the defined rules of GO have been used in multiple cooperative databases, making these databases highly consistent in their queries.

GO analysis of differentially expressed genes between M and JP Fig.1 GO analysis of differentially expressed genes between M and JP. (Ji X, et al. 2020)

Application of GO Analysis

In microbial research, GO analysis can be used for the following purposes,

  • Classification of differential proteins
  • Predicting the function of related proteins
  • Identification of some microbial genes

Service Offering

Our services in GO analysis include,

  • GO annotation analysis
  • GO enrichment analysis
  • Other customized services you require

Turnaround Time

In general, our turnaround time is 2-6 weeks depending on the size of your project.

Advantages of Our Services 

  • We have experienced researchers and professional bioinformatics analysis.
  • We will combine the demands of customers, and negotiate to determine the content of services.
  • We provide fast turnaround, high quality analysis reports at competitive prices to our global customers.
  • We have a well-established quality management system to ensure the quality of our services.

Creative Biogene is an expert in microbial bioinformatics analysis services and has accumulated years of experience in GO analysis. The services we offer are excellent in terms of speed, accuracy and reliability. You can choose us with confidence, we anticipate your presence and look forward to working with you for your cooperation.

If you are interested in our services, please contact us for more details.

Reference

  1. Ji X, et al. (2020). "Metagenomic analysis of gut microbiota modulatory effects of jujube (Ziziphus jujuba Mill.) polysaccharides in a colorectal cancer mouse model." Food & function. 11.1: 163-173.
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