Candida Albicans Genome Editing

Candida albicans

Candida albicans is a common organism that exists widely in nature and also lives harmlessly in the skin or intestines. It is a normal fungus that parasitizes human skin mucous membranes and is also a clinically important conditional pathogenic bacterium. This yeast grows in an uncontrolled manner under certain conditions, especially in immune-compromised individuals, causing mild to fatal fungal infections.

There are five million species of fungi, but only a few hundred can cause human diseases, Candida albicans is one of the most feared. It belongs to one of the four pathogenic fungi that cause high mortality in human beings and is the second most common opportunistic fungal infection in the world. Candida albicans is part of the human intestinal microbiota, but it may cause mucosal infections in healthy individuals and severe opportunistic infections in individuals with weakened immune defenses.

Application of Candida Albicans Genome Editing

Genetic analysis of Candida albicans revealed the determinants of pathogenicity, drug resistance and other unique biological characteristics, as well as the identity of the expected drug target. The genetic engineering research and gene editing of Candida albicans are vital to the development of next-generation antifungal therapies and can also be used to develop targeted drugs.

Application of Candida albicans genome editing- Creative Biogene

Service Offering

Creative Biogene uses two methods to achieve Candida albicans genome editing, they are,

  • Candida albicans genome editing based on Rec
  • Candida albicans genome editing based on CRISPR/Cas9

The specific content of the Candida albicans genome editing service provided by Creative Biogene includes,

  • Candida albicans gene knockout
  • Candida albicans gene knock-in
  • Candida albicans gene activation and inhibition
  • Candida albicans gene point mutation

Turnaround Time

In general, our turnaround time is 4-8 weeks depending on the size of your project.

Advantages of Our Services 

  • Traceless gene editing technology, security is guaranteed.
  • The need for multiple gene knockouts can be realized simultaneously.
  • High gene editing efficiency and recombination efficiency.
  • We can combine the demands of customers, and negotiate to determine the content of services.
  • Short turnaround time and high cost performance.

Creative Biogene has excellent microbiology experts, well-established gene editing platforms, and professional bioinformatics analysis to provide you with a one-stop service in Candida albicans genome editing. We believe that our services will make your project more effective.  

If you are interested in our services, please contact us for more details.


  1. Nguyen N, et al. (2017). "An efficient, rapid, and recyclable system for CRISPR-mediated genome editing in Candida albicans." MSphere. 2.2.
  2. Min K, et al. (2016). "Candida albicans gene deletion with a transient CRISPR-Cas9 system." MSphere. 1.3.
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