Proteomics is derived from the combination of the two words protein and genomics, it refers to "a complete set of proteins expressed by a genome". In 1995, Marc Wikins first proposed the concept of the proteome.
With the continuous emergence of a large amount of DNA sequence data, people realized that it is not enough to attempt to elucidate the phenomenon of life by the genome sequence alone. The forms and activity patterns of the protein itself, such as post-translational modification, protein-protein interaction, and protein structure, need to be resolved by the study of proteomics. Proteomics enables us to study and grasp life phenomena at the molecular level from a comprehensive and holistic perspective, which promotes the understanding of the nature of life phenomena and the branches of life sciences. In addition, proteome research can also provide theoretical basis and solutions for the elucidation and conquering of many kinds of disease mechanisms.
Due to the few types of individual microbial proteins, it has become a breakthrough in proteomics research and has made great progress. At the same time, new concepts such as subproteomics, comparative proteomics, and quantitative proteomics are put forward, which promoted the development of proteomics.
DIA has excellent accuracy and repeatability, which is an important trend in proteomics research. Due to the panoramic data collection and quantification without labeling of protein quantitative DIA products, its main application area is projects with large sample sizes
SILAC technology uses medium containing isotope-labeled essential amino acids to label newly synthesized proteins with stable isotopes during cell growth. Our SILAC service reduces the quantitative error, and it is efficient, stable, sensitivity and small size requirements
iTRAQ is a new in vitro isotope labeling technology，which can accurately quantify and identify all proteins expressed in a genome or all proteins, search for differentially expressed proteins, and reveal their cellular functions.
We use the most advanced LC-MS-MS technology to identify the protein you are interested in. Our three identification methods provide you with a full range of protein identification services.
Post-translational modification plays a key role in a variety of cellular processes, such as cell division, protein breakdown, signal transmission, regulatory processes, gene expression regulation and protein interaction. Our PTM service is efficient and has a short turnaround time
Creative Biogene is a forward-looking research institution and a leading customer service provider in the field of microbial proteomics. Our experienced scientists choose the most suitable experimental strategy and data analysis pipeline according to your samples and research purposes. We use advanced analysis platforms to provide you with results of good reproducibility and high accuracy.
If you are interested in our services, please contact us for more details.