Microbial Isolation & Cultivation

Microbial isolation and cultivation refer to the process of microorganism separating, purifying and cultivating in different media and culture conditions based on the traits and growth characteristics of microorganisms. Microbial isolation and culture technology is widely used in the fields of microbial environmental function research, the elucidation of metabolic pathways, the verification of specific functions, and the application of basic experiments and production practices.

Microorganism Cultivation

The Importance of Microbial Isolation & Cultivation

There are many types of environmental microorganisms, and the total number is huge. An estimation of the number of microbial species is 105-106, but only a few thousand have been isolated in pure culture. Therefore, most microorganisms from the environment resist cultivation in the laboratory. These "uncultivables" account for more than 99% of all microbial species in nature. Phylogenetic analysis of rRNA sequences, especially 16S rRNA sequences, direct sampling from the environment, indicates that uncultivated organisms can be found in almost every taxon within the bacteria and archaea. At present, only a small part of microorganisms in nature can be separated and cultivated, which seriously hinders the research on the laws of microbial life activities and the development of microbial resources.

Considering that different microorganisms have different demands for energy, nutrition as well as physical and chemical conditions, it is necessary to improve the traditional separation and cultivation methods, adopt new isolation and cultivation techniques, improve the culture ability of microorganisms, and cultivate a large number of microorganisms that exist in nature. In this way, we can understand the life laws of microbial cells more comprehensively and accurately, learn the rules of dynamic interaction and mutual coordination between various microorganisms, and then accurately design, finely control and efficiently use environmental microbial technology.

The method of isolating and culturing microorganisms that could not be cultivated before is preferable. Such an approach will change microbiology by opening the door to microbial diversity, thereby revolutionizing pharmaceutical research and development.

Service Offering

Strain Anaerobic Culture

Anaerobic microorganisms thrive where oxygen is depleted and play a crucial role in the carbon cycle, medical health, fermentation industry, and new fuel development, etc. Strain anaerobic culture refers to the culture of microorganisms in an oxygen-free environment. Our company has established a mature anaerobic cultivation system and a complete anaerobic culture platform. We can provide different types of anaerobic bacteria according to your needs. And our services include collection, strain cultivation, isolation, identification and strain preservation, which fully meet your requirements.

Isolation & Cultivation of Specific Bacteria

Microorganisms exist in a mixed state in nature. To obtain the desired strains, they must be isolated. For the cultivation of specific bacteria, one or more special media suitable for the growth of specific bacteria are often used. Our company combining traditional bacterial isolation and cultivation methods with sequencing technology, to provide customers with efficient microbial targeted cultivation services to help customers obtain specific strains.

Our Service Process

The service process of Microbial isolation & cultivation- Creative Biogene

Advantages of Our Services

  • Customize the experimental scheme according to your needs.
  • Experienced researchers and advanced platform.
  • Well-established quality management system

Creative Biogene is a forward-looking research institution and a leading customer service provider in the field of bacterial isolation, purification and cultivation technology. Since its establishment, we have been focusing on the research and utilization of microorganisms, and have rich experience in detection and cultivation. By using advanced high-throughput sequencing technology and mature microbial anaerobic and aerobic culture platform, we have turned the separation and purification of microorganisms into a simple matter.

If you are interested in our services, please contact us for more details.


  1. Rosa A (2016). "Isolation and Cultivation of Anaerobes." Advances in Biochemical Engineering/Biotechnology. 35-53.
  2. Lewis K, et al. (2006). "Isolation and cultivation of microorganisms from natural environments and drug discovery based thereon." U.S. Patent. 7,011,957.
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