Phragmidiothrix Cultivation

Phragmidiothrix has a noded, unbranched, colorless mycelium. The mycelium is over 100 microns in length. They attach and form gray-white clumps. The free end can be larger in diameter than the base, but is not sharp in either direction and varies between 3 and 6 microns in diameter. A very thin, delicate, gelatinous colorless sheath surrounds the free end. This sheath is not inlaid with iron or manganese containing compounds. The cells of Phragmidiothrix vary in size, generally small and disc-shaped, with cell diameters 4-6 times the thickness. The cell wall of the bacteria is distinct and the thickness is uniform throughout the mycelium. Phragmidiothrix reproduces by forming a diaphragm, both transverse and longitudinal in certain areas of the mycelium, resulting in small. This in turn produces small, sarcoid-like aggregates resembling three-dimensional propagating cells. The cells that form the septum may have larger diameters, causing local enlargement of the mycelium. The diameter of the partition formed between the two planes can reach 6 microns. Pure cultures have not been performed on artificial media. Originally found attached to the surface of live Gammarus locusta, it was collected from an anaerobic, H2S-containing contaminated area called "Weisser Grund" or "Todten Grund" in the Bay of Kieler, Germany. The bacterium is not uncommon and has been reported on algae in polluted water in the North Adriatic Sea.

Figure 1. Phragmidiothrix.Figure 1. Phragmidiothrix. (Bergey, D.H., 1985)

Phragmidiothrix Culture Service

Creative Biogene offers customizable Phragmidiothrix strain culture services. This service can help you obtain Phragmidiothrix cultures for subsequent scientific research. This service allows you to skip the complicated and tedious groping of culture conditions, which helps to speed up research on this strain.

Phragmidiothrix multiseptata

Phragmidiothrix multiseptata is the most typical type species of Phragmidiothrix, and its characteristics are consistent with the description of the above genus.

Microbial GMP Production

Creative Biogene's fermentation platform has Good Manufacturing Practices (GMP) and can provide customers with a wide range of high-quality microbial fermentation products such as active pharmaceutical ingredients, enzymes and various fine chemicals. In addition, our microbiology experts have completed the transformation and innovation of traditional processes through continuous breakthroughs in key technologies of microbial fermentation processes, and fully contributed to the smooth delivery of the project.

Production Capacity

Creative Biogene builds a world-class microbial fermentation technology platform, providing a variety of services from strain screening and optimization to fermentation production and product purification. We have many years of rich experience and provide good technical support for microbial GMP production.

Facility Display

As a leader in microbial production, Creative Biogene has comprehensive production process technology and high-volume manufacturing capabilities. Our goal is to help our customers develop streamlined and controlled manufacturing processes and to support customers throughout the entire product development process, from the R&D stage to market launch.

Device Example:

  • Fermentation, centrifugation and filtration upstream process equipment;
  • Fully automatic fermenters ranging in volume from 4,000L to 12,000L with a total capacity of over 100,000 liters;
  • From industrial-scale chromatography systems, membrane systems to larger-scale continuous centrifuges;
  • Recycling and Downstream Equipment;
  • Waste treatment equipment.

Why Choose Us?

The culture of Phragmidiothrix requires specific formulations of growth media for use in cloning, plasmid DNA preparation, and protein expression. Creative Biogene offers a selection of bacterial growth media and custom services for your specific application. If you are interested in our microbial anaerobic and aerobic culture platform, please contact us for more details.


  1. Bergey's Manual of Systematic Bacteriology Book Review Int. J. of Syst. Bact. 1985, p. 165.
For Research Use Only.
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