consultation 

KEGG Analysis

KEGG, whose full name is Kyoto Encyclopedia of Genes and Genomes, was launched in 1995 by Kanehisa Laboratories. Now it has developed into a comprehensive database that integrates genome, chemistry, and system function information. One of the characteristics of the KEGG database is that the gene catalog obtained from the completely sequenced genome is associated with the higher-level cell, species and ecological system functions. It can be applied to query metabolic pathways, enzymes as well as products, and can also query metabolic pathway information of unknown sequences through BLAST alignment.

KEGG Pathway database is the core of KEGG resources. KEGG Pathway is a collection of metabolic pathways, including the following intermolecular interactions and reaction networks, and they are cellular processes, environmental information processing, genetic information processing, human diseases, metabolism, organic systems and drug development. Each category is classified by the system. There are two, three, and four layers and the fourth layer is the specific annotation information of each metabolic pathway diagram.

Reconstructed pathway of galactose metabolism based on metatranscriptomic data by KEGG annotation Fig.1 Reconstructed pathway of galactose metabolism based on metatranscriptomic data by KEGG annotation. (Saminathan T, et al. 2018)

KEGG enrichment analysis of differentially expressed genesFig.2 KEGG enrichment analysis of differentially expressed genes. (Wang W, et al. 2016)

Service Offering

We can understand the differences in the metabolic pathways of the functional genes of the microbial community between samples of different groups by the KEGG pathway database. It offers us a simple and quick method to understand the metabolic process of community samples' environmental adaptation to changes. In addition, we can also provide predictions of the number and composition of functional genes, and give you analysis results with statistical significance and confidence intervals. The KEGG services we offering including these aspects,

  • KEGG annotation analysis
  • KEGG enrichment analysis
  • Other customized services you require

Turnaround Time

In general, our turnaround time is 2-6 weeks depending on the size of your project.

Advantages of Our Services 

  • Our professional researchers have rich experience in KEGG analysis.
  • Our comprehensive and detailed service content allows you to enjoy a one-stop experience.
  • We can customize the analysis items according to your needs.
  • We will feedback progress to customers in time to ensure that your requirements are met.

Creative Biogene is the world's leading bioinformatics company. We are committed to providing customers with advanced microbial analysis services, and the KEGG analysis is one of our specialties. The services we offer are second to none in terms of speed, accuracy and reliability. With high quality and reasonable price, we sincerely look forward to serving you.

If you are interested in our services, please contact us for more details.

References

  1. Saminathan T, et al. (2018). "Metagenomic and metatranscriptomic analyses of diverse watermelon cultivars reveal the role of fruit associated microbiome in carbohydrate metabolism and ripening of mature fruits." Frontiers in plant science. 9: 4.
  2. Wang W, et al. (2016). "Effects of early feeding on the host rumen transcriptome and bacterial diversity in lambs." Scientific Reports. 6: 32479.
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