Enzyme Commission Number
EC 3.4.21.43
Product Overview
High-quality enzyme products.
Well-established quality management system.
Reaction
Selective cleavage of Arg┼Ser bond in complement component C3 α-chain to form C3a and C3b, and Arg┼ bond in complement component C5 α-chain to form C5a and C5b
Function
A complex of complement fragments C4b, C2a and C2b. C2a contains the active site, C2b the site for C4b binding. C2a and C2b are formed by cleavage of proenzyme C2 by complement subcomponent C1s. Cleavage of C5 requires complement fragment C3b which binds C5 and renders it susceptible to cleavage by the C4b,2a complex. Includes former EC 3.4.21.44. Complement component C2a is in peptidase family S1 (trypsin family)
Other name
C3 convertase; C42; C4b,2a; C5 convertase; C423; C4b,2a,3b; C42; C423; complement C.hivin.4.hivin2; complement C3 convertase
Production Methods
Fermentation
Package
on customer request
Applications
Research Use
Storage
Should be stored in a dry and cool place, avoiding high temperature.
Appearance / Form
powder or liquid
Odor
Normal microbial fermentation odour.
WARNINGS
Keep sealed after use every time to avoid microbial infections and inactivation of enzymes until its finish.
Description
Microbial enzymes have been used in a large number of fields, such as chemical, agricultural and biopharmaceutical industries. Our enzyme production services are based on bacteria, fungi, and yeast, from strain selection, optimization, and process development to scale-up production.
