Enzyme Commission Number
EC 2.8.2.35
Product Overview
High-quality enzyme products.
Well-established quality management system.
Reaction
3′-phospho-5′-adenylyl sulfate + [dermatan]-N-acetyl-D-galactosamine = adenosine 3′,5′-bisphosphate + [dermatan]-4-O-sulfo-N-acetyl-D-galactosamine
Systematic Name
3′-phospho-5′-adenylyl sulfate:[dermatan]-N-acetyl-D-galactosamine 4-sulfonotransferase
Function
The sulfation takes place at the 4-position of N-acetyl-D-galactosamine residues of dermatan. D4ST-1 shows a strong preference in vitro for sulfate transfer to IdoUAα(1,3)GalNAcβ(1,4) that is flanked by GlcUAβ(1,3)GalNAcβ(1,4) as compared with IdoUAα(1,3)GalNAcβ(1,4) flanked by IdoUAα(1,3)GalNAcβ(1,4).
Other name
dermatan-specific N-acetylgalactosamine 4-O-sulfotransferase; dermatan-4-sulfotransferase-1; dermatan-4-sulfotransferase 1; D4ST-1; dermatan N-acetylgalactosamine 4-O-sulfotransferase; CHST14 protein; CHST14; 3′-phospho-5′-adenylyl sulfate:[dermatan]-N-acetyl-D-galactosamine 4-sulfotransferase
Production Methods
Fermentation
Package
on customer request
Applications
Research Use
Storage
Should be stored in a dry and cool place, avoiding high temperature.
Appearance / Form
powder or liquid
Odor
Normal microbial fermentation odour.
WARNINGS
Keep sealed after use every time to avoid microbial infections and inactivation of enzymes until its finish.
Description
Microbial enzymes have been used in a large number of fields, such as chemical, agricultural and biopharmaceutical industries. Our enzyme production services are based on bacteria, fungi, and yeast, from strain selection, optimization, and process development to scale-up production.
