Enzyme Commission Number
EC 3.1.8.2
Product Overview
High-quality enzyme products. Well-defined strains can be also provided for our clients to manufacture fermented products in a cost-effective way.
Features
Ready-to-use product, accelerating research progress, enhancing application performance.
Synonyms
DFPase; tabunase; somanase; organophosphorus acid anhydrolase; organophosphate acid anhydrase; OPA anhydrase (ambiguous); diisopropylphosphofluoridase; dialkylfluorophosphatase; diisopropyl phosphorofluoridate hydrolase; isopropylphosphorofluoridase; diisopropylfluorophosphonate dehalogenase
Function
Acts on phosphorus anhydride bonds (such as phosphorus-halide and phosphorus-cyanide) in organophosphorus compounds (including ’nerve gases’). Inhibited by chelating agents; requires divalent cations. Related to EC 3.1.8.1 aryldialkylphosphatase.
Applications
Research and Development
Production Methods
Fermentation
Unit Definition
One unit corresponds to the amount of enzyme which hydrolyzes 1 μmol diisopropyl fluorophosphate per minute at pH 8.1 and 22°C
Reaction
diisopropyl fluorophosphate + H2O = diisopropyl phosphate + fluoride
Specification
On customer requests
Description
In enzymology, a diisopropyl-fluorophosphatase (EC 3.1.8.2) is an enzyme that catalyzes the chemical reaction:diisopropyl fluorophosphate + H2O↔ diisopropyl phosphate + fluoride. Thus, the two substrates of this enzyme are diisopropyl fluorophosphate and H2O, whereas its two products are diisopropyl phosphate and fluoride. This enzyme belongs to the family of hydrolases, specifically those acting on ester bonds phosphoric-triester hydrolases. It employs one cofactor, divalent cation. At least one compound, Chelating agent is known to inhibit this enzyme.
