Products

equine arterivirus serine peptidase

Product Information

Cat #

MEVP-3571

Similar

peptidase

Enzyme Commission Number

EC 3.4.21.114

Product Overview

High-quality enzyme products.
Well-established quality management system.

Reaction

Cleavage of (Glu/Gln)┼(Gly/Ser/Ala) in arterivirus replicase translation products ORF1a and ORF1ab

Systematic Name

Function

In the equine arterivirus (EAV), the replicase gene is translated into open reading frame 1a (ORF1a) and ORF1ab polyproteins. This enzyme is the main viral proteinase and processes five cleavage sites in the ORF1a protein and three in the ORF1b-encoded part of the ORF1ab protein to yield nonstructural proteins (nsp5-nsp12). It combines the catalytic system of a chymotrypsin-like serine peptidase (His-Asp-Ser catalytic triad) with the substrate specificity of a 3C-like serine peptidase (Glu or Gln) at the P1 position and a small amino-acid residue (Gly, Ser or Ala) at the P1′ position. Cleavage of ORF1ab by this enzyme is essential for viral replication. Belongs in peptidase family S32.

CAS No.

Other name

Source

Microorganism

Production Methods

Fermentation

Package

on customer request

Applications

Research Use

Storage

Should be stored in a dry and cool place, avoiding high temperature.

Appearance / Form

powder or liquid

Odor

Normal microbial fermentation odour.

Purity

High Purity

Shelf Life

~12 months

WARNINGS

Keep sealed after use every time to avoid microbial infections and inactivation of enzymes until its finish.

Description

Microbial enzymes have been used in a large number of fields, such as chemical, agricultural and biopharmaceutical industries. Our enzyme production services are based on bacteria, fungi, and yeast, from strain selection, optimization, and process development to scale-up production.

For Research Use Only.

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