Enzyme Commission Number
EC 2.1.1.364
Product Overview
High-quality enzyme products.
Well-established quality management system.
Reaction
S-adenosyl-L-methionine + a [histone H3]-L-lysine4 = S-adenosyl-L-homocysteine + a [histone H3]-N6-methyl-L-lysine4
Systematic Name
S-adenosyl-L-methionine:[histone H3]-L-lysine4 N6-methyltransferase
Function
This entry describes enzymes that catalyse a single methylation of the L-lysine4 residue of histone H3 (H3K4), generating a monomethylated form. This modifications influence the binding of chromatin-associated proteins and result in gene activation or suppression. Some enzymes that catalyse this reaction continue to generate a trimethylated form; these enzymes are classified under EC 2.1.1.354, [histone H3]-lysine4 N-trimethyltransferase.
Other name
KMT7 (gene name); SETD7 (gene name); SET7/9 (gene name); KIAA1717 (gene name)
Production Methods
Fermentation
Package
on customer request
Applications
Research Use
Storage
Should be stored in a dry and cool place, avoiding high temperature.
Appearance / Form
powder or liquid
Odor
Normal microbial fermentation odour.
WARNINGS
Keep sealed after use every time to avoid microbial infections and inactivation of enzymes until its finish.
Description
Microbial enzymes have been used in a large number of fields, such as chemical, agricultural and biopharmaceutical industries. Our enzyme production services are based on bacteria, fungi, and yeast, from strain selection, optimization, and process development to scale-up production.
