Enzyme Commission Number
EC 4.3.2.6
Product Overview
High-quality enzyme products.
Well-established quality management system.
Reaction
γ-L-glutamyl-butirosin B = butirosin B + 5-oxo-L-proline
Systematic Name
γ-L-glutamyl-butirosin B γ-glutamyl cyclotransferase (5-oxo-L-proline producing)
Function
The enzyme catalyses the last step in the biosynthesis of the aminoglycoside antibiotic butirosin B. The enzyme acts as a cyclotransferase, cleaving the amide bond via transamidation using the α-amine of the terminal γ-L-glutamate of the side chain, releasing it as the cyclic 5-oxo-L-proline.
Other name
btrG (gene name); γ-L-glutamyl-butirosin B γ-glutamyl cyclotransferase (5-oxoproline producing)
Production Methods
Fermentation
Package
on customer request
Applications
Research Use
Storage
Should be stored in a dry and cool place, avoiding high temperature.
Appearance / Form
powder or liquid
Odor
Normal microbial fermentation odour.
WARNINGS
Keep sealed after use every time to avoid microbial infections and inactivation of enzymes until its finish.
Description
Microbial enzymes have been used in a large number of fields, such as chemical, agricultural and biopharmaceutical industries. Our enzyme production services are based on bacteria, fungi, and yeast, from strain selection, optimization, and process development to scale-up production.
