Enzyme Commission Number
EC 5.1.1.14
Product Overview
High-quality enzyme products.
Well-established quality management system.
Reaction
(1) isonocardicin C = nocardicin C
(2) isonocardicin A = nocardicin A
Systematic Name
nocardicin-C epimerase
Function
Requires pyridoxal 5′-phosphate. The enzyme, characterized from the bacterium Nocardia uniformis, is involved in the biosynthesis of the monolactam antibiotic nocardicin A. It catalyses the epimerization of the amino group at position 9′ from (S)- configuration to (R)-. The enzyme can act on both isonocardicin A and isonocardicin C, but the in vivo substrate appears to be the latter.
Other name
isonocardicin A epimerase; nocJ (gene name)
Production Methods
Fermentation
Package
on customer request
Applications
Research Use
Storage
Should be stored in a dry and cool place, avoiding high temperature.
Appearance / Form
powder or liquid
Odor
Normal microbial fermentation odour.
WARNINGS
Keep sealed after use every time to avoid microbial infections and inactivation of enzymes until its finish.