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Recombinant ATP Citrate Lyase Active from Human

 Product Information

Cat #
MBS-1167
CAS No.
9067-82-7
Enzyme Commission Number
EC 2.3.3.8
Product Overview
High-quality enzyme products. Well-defined strains can be also provided for our clients to manufacture fermented products in a cost-effective way.
Features
Ready-to-use product, accelerating research progress, enhancing application performance.
Method
Technology
Synonyms
ATP-citric lyase; ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-→acetyl-CoA] (ATP-dephosphorylating); acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating); adenosine triphosphate citrate lyase; citrate cleavage enzyme; citrate-ATP lyase; citric cleavage enzyme; ATP citrate (pro-S)-lyase
Type
Function
The enzyme can be dissociated into components, two of which are identical with EC 4.1.3.34 (citryl-CoA lyase) and EC 6.2.1.18 (citrate—CoA ligase).
Applications
Research Use
Storage
Store at -70°C. Avoid multiple freeze-thaw cycles.
Storage Buffer
Shelf Life
Strains
Baculovirus
Source
Baculovirus
Appearance
Molecular Weight
147 kDa
Color / Form
Instruction
Enzyme Class
Transferases
Production Methods
Fermentation
Activity
Specific Enzyme Activity
Purity
> 90% (SDS-PAGE)
Unit Definition
One unit is defined as the amount of enzyme required to convert 1 pmol of ADP to ATP/min at 37°C.
Amino Acids Sequence
WARNINGS
Shipping
Formula
Reaction
ADP + phosphate + acetyl-CoA + oxaloacetate = ATP + citrate + CoA
Recommendation
Species Reactivity
Contents
Compatibility
Melting Point
Final Titre
Fermentation Time
Recovery Yield
Starting Material
Specification
On customer requests
Substrates
Concentration
Usage And Dosage

 Description

ATP Citrate lyase is an enzyme involved in fatty acid synthesis that generates cytosolic acetyl-CoA and oxaloacetate from Citrate and CoA. ATP Citrate lyase is often upregulated in cancer.

For Research Use Only.
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