Products

Recombinant Thrombin from Human

Product Information

Cat #

MBS-0945

CAS No.

9002-0 4-4

Enzyme Commission Number

EC 3.4.21.5

Product Overview

High-quality enzyme products. Well-defined strains can be also provided for our clients to manufacture fermented products in a cost-effective way.

Features

Ready-to-use product, accelerating research progress, enhancing application performance.

Method

Technology

Synonyms

fibrinogenase; thrombase; thrombofort; topical; thrombin-C; tropostasin; activated blood-coagulation factor II; blood-coagulation factor IIa; factor IIa; E thrombin; β-thrombin; γ-thrombin

Type

Function

Formed from prothrombin. More selective than trypsin and plasmin. In peptidase family S1 (trypsin family).

Applications

Research Use

Storage

−70°C

Storage Buffer

Shelf Life

Strains

HEK293 cells

Source

HEK 293 cells

Appearance

Molecular Weight

Color / Form

Instruction

Enzyme Class

Hydrolases

Production Methods

Fermentation

Activity

Specific Enzyme Activity

Purity

> 95% (SDS-PAGE)

Unit Definition

Amino Acids Sequence

WARNINGS

Shipping

Formula

Reaction

Selective cleavage of Arg┼Gly bonds in fibrinogen to form fibrin and release fibrinopeptides A and B

Recommendation

Species Reactivity

Contents

Compatibility

Melting Point

Final Titre

Fermentation Time

Recovery Yield

Starting Material

Specification

On customer requests

Substrates

Concentration

Usage And Dosage

Description

Thrombin is a serine protease that in humans is encoded by the F2 gene. Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the coagulation cascade, which ultimately results in the reduction of blood loss. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions.

For Research Use Only.

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