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single-stranded DNA cytosine deaminase

 Product Information

Enzyme Class
Hydrolases
Similar
DNA deaminase
Enzyme Commission Number
EC 3.5.4.38
Product Overview
High-quality enzyme products.
Well-established quality management system.
Reaction
cytosine in single-stranded DNA + H2O = uracil in single-stranded DNA + NH3
Systematic Name
single-stranded DNA cytosine aminohydrolase
Function
The enzyme exclusively catalyses deamination of cytosine in single-stranded DNA. It preferentially deaminates five-nucleotide bubbles. The optimal target consists of a single-stranded NWRCN motif (W = A or T, R = A or G). The enzyme initiates antibody diversification processes by deaminating immunoglobulin sequences.
CAS No.
Other name
AID; activation-induced deaminase; AICDA (gene name); activation-induced cytidine deaminase
Source
Microorganism
Production Methods
Fermentation
Package
on customer request
Applications
Research Use
Storage
Should be stored in a dry and cool place, avoiding high temperature.
Appearance / Form
powder or liquid
Odor
Normal microbial fermentation odour.
Purity
High Purity
Shelf Life
~12 months
WARNINGS
Keep sealed after use every time to avoid microbial infections and inactivation of enzymes until its finish.
For Research Use Only.
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