Products

Tacrolimus

Product Information

Cat #

MFTP-120

CAS No.

104987-11-3

Enzyme Commission Number

Product Overview

Tacrolimus, also known as fujimycin or FK506, is an immunosuppressive drug used mainly after allogeneic organ transplant to lower the risk of organ rejection. It achieves this by inhibiting the production of interleukin-2, a molecule that promotes the development and proliferation of T cells, which are vital to the body's learned (or adaptive) immune response. Tacrolimus is also used in the treatment of other T cell-mediated diseases such as eczema (for which it is applied to the skin in a medicated ointment), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, Kimura's disease, and the skin condition vitiligo.

Features

Ready-to-use product, accelerating research progress, enhancing application performance.

Method

Technology

Synonyms

Type

Function

Applications

Industrial Applications

Storage

Storage Buffer

Shelf Life

Strains

Streptomyces spp.

Source

Appearance

Molecular Weight

Color / Form

Instruction

Enzyme Class

Production Methods

Fermentation

Activity

Specific Enzyme Activity

Purity

Unit Definition

Amino Acids Sequence

WARNINGS

Shipping

Timely shipping by optional means

Formula

Reaction

Recommendation

Species Reactivity

Contents

Compatibility

Melting Point

Final Titre

1.5g/L

Fermentation Time

240±24hrs

Recovery Yield

>70%

Starting Material

Specification

Standard and Custom Specifications

Substrates

Concentration

Usage And Dosage

Description

Tacrolimus was first discovered in 1987 from the fermentation broth of a Japanese soil sample that contained the bacterium Streptomyces tsukubaensis.

For Research Use Only.

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